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. 2018 Jun 14;9:718. doi: 10.3389/fphys.2018.00718

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Copyright © 2018 Martinez, Walton, Bayer, Haïssaguerre, Vigmond, Hocini and Bernus.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of ischemia on transmural APD heterogeneity. Endocardial and epicardial AT and APD maps and corresponding AP traces as shown in Figure 2 for ENDO (A), EPI (B), and PF (C) pacing. Stimulation sites are indicated by (^∗), arrows show origins of early activation for PF stimulation in C, dashed arrows indicate origin of breakthrough, and black circles show PMJs location on AT and APD maps for all pacing sites. Isochrones are 5 ms spacing for endocardial maps and 10 ms for epicardial maps.