Table 2.
Relationships between PNI and patient characteristics
| Characteristics | PNI (n=243) | ||
|---|---|---|---|
| ≤48.5 (n=90), n (%) | >48.5 (n=153), n (%) | P value | |
| Age (years) | |||
| ≤60 | 48 (53.3) | 104 (68.0) | 0.023 |
| >60 | 42 (46.7) | 49 (32.0) | |
| Sex | |||
| Female | 30 (33.3) | 62 (40.5) | 0.265 |
| Male | 60 (66.7) | 91 (59.5) | |
| Primary tumor site | |||
| Colon | 59 (65.6) | 95 (62.1) | 0.588 |
| Rectum | 31 (34.4) | 58 (37.9) | |
| Primary tumor size (cm) a | |||
| ≤4 | 40 (44.4) | 74 (48.4) | 0.101 |
| >4 | 37 (41.1) | 42 (27.5) | |
| Not available | 13 (14.4) | 37 (24.2) | |
| T stage | |||
| 1-3 | 62 (68.9) | 97 (63.4) | 0.385 |
| 4 | 28 (31.1) | 56 (36.6) | |
| N stage | |||
| 0 | 39 (43.3) | 66 (43.1) | 0.976 |
| 1-2 | 51 (56.7) | 87 (56.9) | |
| Histological grade | |||
| Well/moderate | 75 (83.3) | 133 (86.9) | 0.441 |
| Poor | 15 (16.7) | 20 (13.1) | |
| Size of liver metastases (cm) | |||
| ≤2.5 | 50 (55.6) | 81 (52.9) | 0.693 |
| >2.5 | 40 (44.4) | 72 (47.1) | |
| Number of liver metastases | |||
| Single | 46 (51.1) | 71 (46.4) | 0.478 |
| Multiple | 44 (48.9) | 82 (53.6) | |
| Extrahepatic metastasis | |||
| Yes | 7 (7.8) | 14 (9.2) | 0.713 |
| No | 83 (92.2) | 139 (90.8) | |
| Hepatic resection timing | |||
| Metachronous | 31 (34.4) | 87 (56.9) | 0.001 |
| Synchronous | 59 (65.6) | 66 (43.1) | |
| Chemotherapy regimen before hepatic resection | |||
| Yes | 32 (35.6) | 46 (30.1) | 0.376 |
| No | 58 (64.4) | 107 (69.9) | |
| Chemotherapy regimen after hepatic resection | |||
| Yes | 63 (70.0) | 121 (79.1) | 0.111 |
| No | 27 (30.0) | 32 (20.9) | |
| RFA therapy b | |||
| Yes | 10 (11.1) | 18 (11.8) | 0.878 |
| No | 80 (88.9) | 135 (88.2) | |
| CEA level (ng/ml) c | |||
| ≤5 | 40 (44.4) | 55 (35.9) | 0.190 |
| >5 | 50 (55.6) | 98 (64.1) | |
| CA19-9 level (U/ml) d | |||
| ≤37 | 61 (67.8) | 113 (73.9) | 0.310 |
| >37 | 29 (32.2) | 40 (26.1) | |
a Data of 193 patients were available
b Radiofrequency ablation therapy within 3 months before or after hepatic resection
c Carcinoembryonic antigen before hepatic resection
d Cancer antigen 19-9 before hepatic resection