Skip to main content
. 2018 Apr 16;7(6):2581–2591. doi: 10.1002/cam4.1491

Figure 1.

Figure 1

Relative miR‐541 expression levels in SCLC tissue samples and SCLC cell lines, and inhibition of SCLC cell proliferation by miR‐541 overexpression. (A) According to the qRT‐PCR results, the miR‐541 expression levels were significantly lower in the cancerous tissues (n = 15) than in the adjacent normal tissues (n = 15) of patients with SCLC. Every test was carried out in triplicate, and n = 3 for each tissue sample. (B) The miR‐541 expression levels were lower in the SCLC cells than in the normal human bronchial epithelial cells (n = 3 for each cell line). (C) Successful miR‐541 overexpression in SK‐MES‐1 cells induced by miR‐541‐mimics. Cells transfected with miR‐541‐scramble served as the control cells (n = 3 for each cell group). (D) Verification of miR‐541 overexpression in H226 cells. Cells transfected with miR‐541‐scramble served as the control cells (n = 3 for each cell group). (E, F) The OD450 values were lower in the miR‐541‐overexpressing SK‐MES‐1 and H226 cells than in the control cells at 24, 48, and 72 h (n = 3 for each cell group). OD450, optical density at 450 nm.