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. 2018 Apr 16;7(6):2581–2591. doi: 10.1002/cam4.1491

Figure 6.

Figure 6

HMGA2 overexpression weakened the inhibitory effects of miR‐541 on the migration and invasion capabilities of the SCLC cell lines. (A, E) The migration capacity was significantly higher in the miR‐541/lenti‐HMGA2 SK‐MES‐1 cells than in the control cells. The migration distance (μm) of the SK‐MES‐1 cells was quantified (n = 3 for each cell group). (B, F) Compared with the control cells, the miR‐541/lenti‐HMGA2 H226 cells presented with a higher migration ability. The migration distance (μm) of the H226 cells was quantified (n = 3 for each cell group). (C, G) The transwell invasion assay results revealed that invasion ability was significantly increased in the miR‐541/lenti‐HMGA2 SK‐MES‐1 cells. The quantified data are presented as the number of invading cells per HPF (n = 3 for each cell group). (D, H) The miR‐541/lenti‐HMGA2 H226 cells also demonstrated a higher invasion capacity. The quantified data are presented as the number of invading cells per HPF (n = 3 for each cell group). HPF, high‐power field.