Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Identification of 2‐(methoxymethyl)pyrimido[1,2‐a]benzimidazol‐4‐ol, GMP‐1 as competitive inhibitor of Tom70‐Hsp90 interactions. A, Chemical structure of GMP‐1. B, Dot‐blot assay of interactions between human Tom70 protein and Hsp90 peptide conjugated to HRP (C90‐HRP) in the presence of DMSO and 100 μmol/L of GMP‐1. C, Dose‐dependent inhibition of Tom70‐ C90‐HRP interactions by GMP‐1. IC 50 was calculated as a mean value of 3 independent experiments
