Figure 3.
Effect of GMP‐1 treatment in drosophila expressing Aβ1‐42 variants in CNS. A, Mobility climbing assay in Aβ1‐42‐expressing flies in the presence of DMSO or 50 μmol/L of GMP‐1. Six independent measurements were performed. B, Viability assay of T‐Aβ1‐42 flies growing at permissive 18°C and non‐permissive 25°C temperatures in the tubes with added DMSO or increasing concentrations of GMP‐1. Bars represent percentage of T‐Aβ1‐42 homozygotes F1 offsprings to the total number of hatched flies. Quadruplicate measurements were performed **P < 0.01, n=4