Skip to main content
. 2018 Jun 20;14(6):e8124. doi: 10.15252/msb.20178124

Figure 2. Application of MOFA to a study of chronic lymphocytic leukaemia.

Figure 2

  • A
    Study overview and data types. Data modalities are shown in different rows (D = number of features) and samples (N) in columns, with missing samples shown using grey bars.
  • B, C
    (B) Proportion of total variance explained (R 2) by individual factors for each assay and (C) cumulative proportion of total variance explained.
  • D
    Absolute loadings of the top features of Factors 1 and 2 in the Mutations data.
  • E
    Visualization of samples using Factors 1 and 2. The colours denote the IGHV status of the tumours; symbol shape and colour tone indicate chromosome 12 trisomy status.
  • F
    Number of enriched Reactome gene sets per factor based on the gene expression data (FDR < 1%). The colours denote categories of related pathways defined as in Appendix Table S2.