Figure 2.
Effect of dexamethasone (DEX) and cortisol on P‐gp and breast cancer resistance protein (BCRP) protein levels in first trimester human placental villous explants. (A&B) Western blot analysis of P‐gp and BCRP levels in first trimester placental explants (n = 6 placentae/group) treated with DEX (A; 10−6 mol/L), cortisol (B; 10−6 mol/L) or VEH for 48 hour. Corresponding mean P‐gp (C&D) or breast cancer resistance protein (BCRP) (E&F) expression relative to β‐actin *P < .05, **P < .01 vs VEH. Data are presented as mean ± SEM