Table 2.

Mantel tests of correlations between subpopulation‐level metabolic, genetic, and environmental distances. Chemical distance matrix obtained through Analysis of Similarities (ANOSIM) using 377 metabolites. Genetic distance matrix consists of linearized F _ST values calculated from 1,171 reference (putatively neutral) SNPs. Site‐level means of temperature at collection (Tcol) and precipitation of driest month (Bio14) used for matrices of Euclidean distances, and geographic distance among sites calculated from a X, Y coordinate system. Vertical bar denotes partial Mantel's test controlling for third matrix right of “|”

Mantel formula	Pearson r	p (r ≤ 0)
Metabolic distance versus geographic distance	.51134369	.02750275
Genetic distance versus geographic distance	.70352647	.00110011
Metabolic distance versus genetic distance	.3340171	.0670067
Metabolic distance versus Tcol	.64711201	.00050005
Metabolic distance versus Bio14	.41785384	.05830583
Metabolic distance versus genetic distance | geographic distance	−.04212434	.57645765
Metabolic distance versus genetic distance | Tcol	−.26949309	.88438844
Metabolic distance versus genetic distance | Bio14	.2555054	.1271127