Table 3.
Characteristics | Total (N = 15,389) | Premenopausal (N = 8395) | Postmenopausal (N = 6994) | P value | |||
---|---|---|---|---|---|---|---|
N | % | N | % | N | % | ||
Tumor histology | |||||||
Carcinoma in situ | 801 | 5.20 | 413 | 4.92 | 388 | 5.55 | 0.053a |
Invasive carcinoma | 14,008 | 90.97 | 7712 | 91.86 | 6296 | 90.02 | |
Missing data | 580 | 3.77 | 270 | 3.22 | 310 | 4.43 | |
Axillary lymph nodes metastasis | |||||||
Yes | 6584 | 42.76 | 3612 | 43.03 | 2972 | 42.49 | 0.914a |
No | 7210 | 46.82 | 3962 | 47.19 | 3248 | 46.44 | |
Missing data | 1595 | 10.36 | 821 | 9.78 | 774 | 11.07 | |
No. of positive axillary lymph nodes | |||||||
0 (N0) | 7210 | 46.82 | 3962 | 47.19 | 3248 | 46.44 | 0.068a |
1–3 (N1) | 4125 | 26.79 | 2285 | 27.22 | 1840 | 26.31 | |
4–9 (N2) | 1572 | 10.21 | 877 | 10.45 | 695 | 9.94 | |
≥10 (N3) | 887 | 5.76 | 450 | 5.36 | 437 | 6.25 | |
Missing data | 1595 | 10.36 | 821 | 9.78 | 774 | 11.07 | |
Lymphovascular invasion | |||||||
Yes | 270 | 1.75 | 155 | 1.85 | 115 | 1.64 | 0.099a |
No | 6873 | 44.64 | 3594 | 42.81 | 3279 | 46.88 | |
Missing data | 8246 | 53.55 | 4646 | 55.34 | 3600 | 51.47 | |
Tumor grade | |||||||
I | 554 | 3.60 | 292 | 3.48 | 262 | 3.75 | 0.588a |
II | 5384 | 34.97 | 2776 | 33.07 | 2608 | 37.29 | |
III | 1893 | 12.29 | 1002 | 11.94 | 891 | 12.74 | |
Uncertain | 1546 | 10.04 | 785 | 9.35 | 761 | 10.88 | |
Missing data | 5988 | 38.89 | 3527 | 42.01 | 2461 | 35.19 | |
ER+/PR+ | |||||||
Yes | 7269 | 50.46 | 4236 | 40.43 | 2828 | 41.25 | <0.0001a |
No | 7324 | 45.21 | 3795 | 53.35 | 3731 | 52.56 | |
Missing data | 796 | 4.34 | 364 | 6.22 | 435 | 6.19 | |
ER+/PR− | |||||||
Yes | 1722 | 8.29 | 696 | 14.20 | 993 | 14.41 | <0.0001a |
No | 12,871 | 87.21 | 7321 | 79.40 | 5553 | 79.40 | |
Missing data | 796 | 4.50 | 378 | 6.41 | 448 | 6.19 | |
ER−/PR+ | |||||||
Yes | 1722 | 5.28 | 443 | 3.33 | 233 | 14.41 | <0.0001a |
No | 12,871 | 90.22 | 7574 | 90.26 | 6313 | 79.40 | |
Missing data | 796 | 4.50 | 378 | 6.41 | 448 | 6.19 | |
ER−/PR− | |||||||
Yes | 4916 | 31.40 | 2636 | 35.72 | 2498 | 34.69 | <0.0001a |
No | 9677 | 64.26 | 5395 | 58.06 | 4061 | 59.12 | |
Missing data | 796 | 4.34 | 364 | 6.22 | 435 | 6.19 | |
HER2 status | |||||||
Yes | 2143 | 13.92 | 1132 | 13.48 | 1011 | 14.46 | 0.015a |
No | 8063 | 52.36 | 4496 | 53.56 | 3567 | 51.00 | |
Uncertain | 2475 | 16.07 | 1257 | 14.97 | 1218 | 17.41 | |
Missing data | 2708 | 17.59 | 1510 | 17.99 | 1198 | 17.13 | |
Triple‐negative | |||||||
Yes | 2372 | 15.40 | 1279 | 15.24 | 1093 | 15.63 | 0.502a |
No | 13,017 | 84.54 | 7116 | 84.76 | 5901 | 84.37 | |
P53 status | |||||||
Yes | 4213 | 27.36 | 2152 | 25.63 | 2061 | 29.47 | <0.0001a |
No | 2304 | 14.96 | 1060 | 12.63 | 1244 | 17.79 | |
Missing data | 8872 | 57.62 | 5183 | 61.74 | 3689 | 52.75 | |
Ki67 | |||||||
≥14 | 4772 | 30.99 | 2534 | 30.18 | 2238 | 32.00 | 0.715a |
14 | 2712 | 17.61 | 1452 | 17.30 | 1260 | 18.02 | |
Missing data | 7905 | 51.34 | 4409 | 52.52 | 3496 | 49.99 | |
ER status | |||||||
Yes | 8802 | 59.14 | 4965 | 54.86 | 3837 | 29.47 | <0.0001a |
No | 5816 | 36.70 | 3081 | 39.10 | 2735 | 17.79 | |
Missing data | 771 | 4.16 | 349 | 6.03 | 422 | 52.75 | |
PR status | |||||||
Yes | 4772 | 55.76 | 4681 | 43.78 | 3062 | 32.00 | <0.0001a |
No | 2712 | 39.93 | 3352 | 50.03 | 3499 | 18.02 | |
Missing data | 7905 | 4.31 | 362 | 6.19 | 433 | 49.99 |
Chi‐square test.