Table 4.
Spearman correlations between markers of inflammation and monoamine metabolism in patients vs. controls.
| Neopterin | Kyn/Trp | Phe/Tyr | ||||
|---|---|---|---|---|---|---|
| Patients | Controls | Patients | Controls | Patients | Controls | |
| IFN-y | 0.31*** | 0.35*** | 0.17** | 0.34*** | 0.05 | −0.11 |
| IL-6 | 0.20** | 0.28** | 0.19** | 0.15 | −0.14* | −0.06 |
| TNF-α | 0.33*** | 0.26*** | 0.32*** | 0.27* | 0.04 | −0.04 |
| CRP | 0.23*** | 0.25*** | −0.01 | 0.1 | −0.04 | −0.05 |
| Neopterin | 1 | 1 | 0.43*** | 0.27*** | 0.17** | −0.07 |
*
p < 0.05;
**
p < 0.01;
***
p < 0.001. Trp, tryptophan; Kyn, kynurenine; Tyr, tyrosine; Phe, phenylalanine; IFN-y, interferon gamma; IL, interleukin; TNF-α, tumor necrosis factor alpha; CRP, C-reactive protein.