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. 2018 Mar 23;12:84–87. doi: 10.1016/j.idcr.2018.03.016

Table 1.

Selected Laboratory Values.

Test Results
Cerebrospinal Fluid Studies
 Color/Appearance Colorless, clear
 Red Blood Cell Count Tube 1 429 (Tube 4 69)
 Nucleated Cell Count 197 (Differential: 1% Polymorphonuclear cells, 81% Lymphocytes, 9% Monocytes, 9% Other (plasma cells)
 Glucose 60
 Protein 121
 Gram Stain and Culture No organisms on gram stain and no growth at 48 hours on culture
 Enterovirus PCR No DNA sequences detected
 Herpes Simplex Virus I PCR No DNA sequences detected
 Herpes Simplex Virus II PCR No DNA sequences detected
 Varicella Zoster Virus PCR No DNA sequences detected
 Epstein-Barr Virus PCR No DNA sequences detected
 Cytomegalovirus PCR No DNA sequences detected
 Lyme IgM, IgG Western Blot No bands detected
 Cryptococcus Antigen Negative
 VDRL Non Reactive
 Powassan IgM Capture ELISA Positive
 Powassan PRNT 64 (POS Control > 320)
 Serum West Nile IgM and IgG Ab: <0.90, <1.30 (negative)
 Fungal Smear and Culture Calcofluor White Stain without yeast or fungal elements identified; culture with no fungus isolated at 4 weeks
 AFB Smear and Culture No AFB isolated at 6 weeks
 Pathology Review “Heterogeneous population of lymphoid cells, plasmacytoid lymphocytes and plasma cells which may be reactive in nature, but couldn't exclude a lymphoproliferative process”
 Eastern Equine Encephalitis Virus Eastern Equine IgG <1:4 (Antibody Not Detected)
 Antibody Panel, IFA Eastern Equine IgM <1:4 (Antibody Not Detected)
 Western Equine Encephalitis Virus Western Equine IgG <1:4 (Antibody Not Detected)
 Antibody Panel, IFA Western Equine IgM <1:4 (Antibody Not Detected)
 California Encephalitis Virus Antibody California IgG <1:4 (Antibody Not Detected)
 Panel, IFA California IgM <1:4 (Antibody Not Detected)
 St. Louis Encephalitis Virus Antibody St. Louis IgG <1:4 (Antibody Not Detected)
 Panel, IFA St. Louis IgM <1:4 (Antibody Not Detected)



Serum Studies
 Powassan IgM Capture ELISA Positive
 Powassan PRNT 2660 (POS Control > 320)
 Lyme Reflex 0.65 Index (negative)
 Babesia microti IgM, IgG <1:20, <1:64 (negative)
 Blood Parasite Prep, Thick Smear for Blood Parasite None seen
 Anaplasma Phagocytophilium PCR Not Detected
 Anaplasma Phagocytophilium IgM, IgG <1:20, <1:64 (negative)
 Mycoplasma pneumonia IgM 0.43 (negative)
 Mycoplasma pneumonia IgG 0.20 (negative)
 Urine Legionella Antigen Negative
 Quantiferon Gold Nil 0.094 (no preexisting immune response)
Mitogen Nil 0.790 (healthy immune response)
Ag Nil -0.041 (negative for TB)



 Plasma Herpes I and II PCR Negative
 VZV PCR Negative

Abbreviations: PCR Polymerase Chain Reaction; CSF = Cerebral Spinal Fluid; VDRL = Venereal Disease Research Laboratory; ELISA = enzyme-linked immunosorbent assay; PRNT = Plaque Reduction Neutralization Test; IFA = Immunofluorescence Assay.