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. 2018 May 23;8(12):3380–3391. doi: 10.7150/thno.24017

Figure 4.

Figure 4

Representative imaging of a mouse with Panc-1TD at the left upper flank (orange arrows) and Panc-1WT tumor at the right upper flank (yellow arrows). (A) Baseline 68Ga-DOTATOC PET imaging shows significantly higher tracer uptake in the Panc-1TD compared to Panc-1WT tumor. (B) Multispectral optical imaging with radioisotopic phosphor screen 2 days after injection of 90Y-DOTATOC shows significant uptake in the Panc-1TD tumor while the uptake in Panc-1WT was at the background level. (C) Eighteen days after 90Y-DOTATOC treatment, Panc-1TD tumor completely disappeared from the left upper flank. The tumor bed did not demonstrate 68Ga-DOTATOC uptake above background level. Panc-1WT tumor continued to grow but, as expected, did not demonstrate any uptake above background. K: kidney; B: bladder.