Table 1.
miRNA expression profiling in SS patients.
| miRNA | miRNA source | Expression | Reference |
|---|---|---|---|
| miR-300, miR-609, miR-3162-3p, miR-4701-5p | Monocytes | Upregulated | (Williams et al. [81]) |
| miR-181a | SG | Upregulated | (Kapsogeorgou et al. [53]) |
| miR-200b | SGEC | ||
| miR-223 | PBMCs | ||
| let-7b | SGEC | Downregulated | |
| miR-146a/b | PBMCs | Upregulated | (Zilahi et al. [74]) |
| miR-17-92 | MSG | Downregulated | (Alevizos and Illei [70]) |
| miR-144-5p, miR-34a-5p, miR-425-3p/-5p, miR-145-5p, miR-21-3p, miR-18a-5p, miR-769-5p, miR-190a, miR-15a-5p, miR-106a-5p, miR-424-3p, miR-20b-5p, miR-16-1-3p, let-7e-5p, let-7d-5p, miR-126-3p/-5p, miR-186-5p, miR-20a-5p, miR-146a-5p, miR-484, miR-191-5p, miR-26a-5p, miR-222-3p | PBMCs | Upregulated | (Chen et al. [75]) |
| miR-150-5p | Downregulated | ||
| miR-155-5p, miR-222-3p, miR-146a-5p, miR-28-5p | T lymphocytes | Upregulated | (Wang-Renault et al. [78]) |
| let-7d-3p, miR-30c-5p, miR-378a-3p | Downregulated | ||
| miR-222-3p | B lymphocytes | Upregulated | |
| miR-378a-3p, miR-26a-5p, miR-30b-5p, miR-19b-3p | Downregulated | ||
| miR-181a, miR-16 | SG | Downregulated | (Wang et al. [82]) |
| miR-146a | PBMCs | Upregulated | (Shi et al. [76]) |
| miR-155 | Downregulated | ||
| miR-146a, miR-155 | PBMCs | Upregulated | (Pauley et al. [77]) |
| miR-181a | PBMCs | Upregulated | (Peng et al. [83]) |
| miR-155, miR-181a | SGEC | Upregulated | (Le Dantec et al. [26]) |
SG: salivary glands; SGEC: cultured salivary glands epithelial cells; PBMCs: peripheral blood mononuclear cells; MSG: minor salivary glands.