Table 4.
Summary table of the results for the mouse micronucleus test.
| Groups (mg/kg bw) |
Sampling time (hour) | Total number of PCEs analyzed | MPCE (per 4000 PCE) |
PCE/NCE | ||
|---|---|---|---|---|---|---|
| Mean | ±SD | Mean | ±SD | |||
| Negative control 0 | 24 | 20000 | 4.40 | 1.14 | 1.13 | 0.04 |
| 500 | 24 | 20000 | 4.60 | 0.55 | 1.09 | 0.12 |
| 1000 | 24 | 20000 | 4.60 | 1.14 | 1.06 | 0.08 |
| 2000 | 24 | 20000 | 5.20 | 0.84 | 0.91 | 0.03 |
| Positive control 60 | 24 | 20000 | 122.80∗∗ | 6.02 | 0.46 | 0.10 |
|
| ||||||
| Negative control 0 | 48 | 20000 | 4.40 | 0.89 | 1.12 | 0.12 |
| 2000 | 48 | 20000 | 5.20 | 1.30 | 0.94 | 0.10 |
Positive control: cyclophosphamide.
Negative control: 1% aqueous methylcellulose.
∗∗: p < 0.01 to the concurrent negative control and to the historical control.