Table 3.

Examples of veterinary autoinflammatory diseases that may be of interest for future study of the role of the inflammasome in these conditions. List is based on Gershwin, 2007, and the Merck Veterinary Manual. In each of these cases, research on human and/or mouse systems has examined potential links between the corresponding disease and inflammasome pathways. Note that inflammasome mechanisms are not necessarily the primary cause of disease, but rather may be linked to the diseases in mice or humans in a variety of possible ways. For a review of autoinflammatory diseases linked to human and rodent inflammasomes, see Shaw et al. (2011).

Disease Name
SLE (Systemic lupus erythematosus)
Immune-mediated thrombocytopenia
Myasthenia gravis
Diabetes mellitus
Inflammatory bowel disease (chronic enteropathies)
Contact allergic dermatitis