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. 2018 Jun 20;16:171. doi: 10.1186/s12967-018-1544-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — 3-year DFS was lower in patients who had more CTCs (a), the filled black columns represent the 3-year DFS of patients who had CTCs no more than the cut-off value, and the empty white columns represent 3-year DFS of patients who had CTC more than the cutoff value. Patients who have ≥ 5 CTCs/7.5 ml blood pre-operatively had shorter DFS (b, d) and OS (c, e)