Table 1.
Weighted Plasmodium falciparum results showing the validation of rapid diagnostic test to detect parasitaemia using thick film microscopy by experienced local technicians, among healthy children in northern Uganda
| Thick film microscopy | Total | ||
|---|---|---|---|
| Negative | Positive | ||
| RDT | |||
| Negative | 46.9% (n = 391) | 0.74% (n = 10) | 47.6% (n = 401) |
| Positive | 20.4% (n = 213) | 32.0% (n = 327) | 52.4% (n = 540) |
| Total | 67.3% (n = 604) | 32.7% (n = 337) | 100% (N = 941) (Nweighted = 2,740,700) |
65 subjects who were missing complete malaria data (48 missing both RDT and thick malaria microscopy; 16 missing thick, and 1 missing RDT) were excluded from further analysis. The percentages in each cell are weighted back to the population of size 2,740,700 based on 942 participants with data; the numbers in parentheses are the numbers of individuals with both RDT and thick film microscopy data. Using results from thick malaria microscopy performed by experienced local technicians to validate RDT, the sensitivity was 97.8% (95.8–99.7%) and specificity was 69.7% (43.4–96.1%)