Table 3.
Lean (n = 6 rats) |
Obese (n = 6 rats) |
Diabetic (n = 6 rats) |
ANOVA p-value |
|
---|---|---|---|---|
3-point bending† | ||||
Tissue modulus (GPa) | 18.3 ± 0.7 | 18.5 ± 0.6 | 15.4 ± 0.8a,b | 0.013 |
Yield stress (MPa) | 251 ± 2 | 245 ± 14 | 182 ± 11a,b | 0.003 |
Ultimate stress (MPa) | 280 ± 5 | 276 ± 7 | 246 ± 9a,b | 0.015 |
Uniaxial tension | ||||
Tissue modulus (GPa) | 18.1 ± 1.6 | 14.8 ± 1.3 | 0.141 | |
Yield stress (MPa) | 79 ± 10 | 72 ± 10 | 0.631 | |
Yield strain (%) | 0.33 ± 0.02 | 0.25 ± 0.02a | 0.018 | |
Ultimate stress (MPa) | 92 ± 10 | 92 ± 12 | 0.792 | |
Ultimate strain (%) | 1.30 ± 0.05 | 0.89 ± 0.04a | 0.022 |
† Tissue material properties from 3-point bend tests were derived using beam theory equations; strain derivations are only valid in the pre-yield region of the stress-strain curve, so yield and post-yield strains are not reported
a p < 0.05 vs. control by posthoc test
b p < 0.05 vs. obese by posthoc test