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Brillouin measurements of normal population. (a) Central cornea Brillouin frequency values of normal individuals in an age range of 15–70. (b) Diurnal change of a healthy volunteer. Within 1 h after wake-up, the hydration level of corneal stroma is stabilized, so are the central corneal thickness (CCT) and Brillouin frequency. The magnitude of frequency variation during day time is less than the instrument's sensitivity of ±10 MHz.
