TABLE II. Summary of the antimony intralesional infiltration therapy.
Number of infiltrations (median, IQR) | 7 (5-8) |
Total volume of Glucantime® infiltrated (median, IQR), mL | 27.7 (16.4-46.4) |
Total antimony dose infiltrated (median, IQR), mg | 2243 (1328-3.758) |
Treatment duration - days between the first and the last infiltration (median, IQR), days | 43 (28-52) |
Time until cure (median, IQR), weeks | 7 (6-13) |
Interval between infiltrations (mean, SD), days | 7.6 ± 2.2 |
Lost to follow-up, n (%) | 0 (0) |
Adverse events | |
Local bacterial infection, n (%) | 7 (13.2) |
Severe adverse event, n (%) | 1 (1.9) |
Local irritation (erythema/oedema/itching), n (%) | 53 (100) |
Local vesicles/bullae, n (%) | 2 (3.7) |
Outcomes | |
Cured patients at the 45-day visit, n (rate, 95%CI) | 32 (60%, 7-72%) |
Cured patients at three months, n (%) | 46 (87%, 75-94% |
Cured patients at six months, n (%) | 46 (87%, 75-94%) |
Relapse at six months | 1/46 (2.2) |
IQR: 25-75% interquartile range; SD: standard deviation; 95% CI: 95% confidence interval.