Figure 1.

Demographic scenario and distribution of fitness effect (DFE) parameters used in the simulations. N-high is set to 10⁵ individuals, and N-low is set to 10⁴ individuals for the reference scenarios, and 10³ individuals for the ‘severe bottlenecks’ scenarios. DFE ‘A’ describes the reference DFE we use in the simulations, which did not include a positive component. DFE ‘B’ presents a change in the shape of the negative DFE, modelled as a gamma distribution, and DFE ‘C’ contains a positive DFE component. α and μ, respectively, stand for the shape and the mean parameter of a gamma distribution. (Online version in colour.)