Table 2.

Overview of selected lipidomics MS analysis tools. “Quantitation” indicates whether the software reports quantitative values. “Structure” specifies if the tool reports results based on the lipid molecular species level, i.e., providing information of constituent chains and/or sn-positions. “Customizable” stands for customization options for self-defined lipid species and potential extensibility.

Name	Type	Quantitation	Structure	Customizable	Availability	URL
ALEX	shotgun	yes	no	yes	free	http://www.msLipidomics.info
AMDMS-SL	shotgun	yes	yes	yes	free	https://pharmacometabolomics.duhs.duke.edu/resources-tools/sanfordburnham-medical-research-institute
LDA	LC	yes	no	yes	free	http://genome.tugraz.at/lda
LipidBlast	both	no	yes	yes	open-source	http://fiehnlab.ucdavis.edu/projects/LipidBlast/
LipidQA	shotgun	yes	yes	no	free	http://lipidqa.dom.wustl.edu/
Lipid Search	LC	yes	yes	no	commercial	marketed by Thermo Fisher Scientific
LipidXplorer	shotgun	yes	yes	yes	open-source	https://sourceforge.net/projects/lipidxplorer