. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Trends Immunol. 2018 Jan 31;39(3):222–239. doi: 10.1016/j.it.2017.12.001

Table 2.

The major NK receptor-ligand pairs in mice.

Mouse inhibitory receptor-ligand pairs		Mouse activating receptor-ligand pairs
Inhibitory receptor	Ligand	Activating receptor	Ligand
Ly49A	H-2D^b, D^d, D^k, D^p and H2-M3	Ly49D	MHC H-2D^d
Ly49C	H-2K^b, -K^d, D^k, D^d, D^b, D^k, m157	Ly49H	MCMV m157
Ly49F	H2-D^d	Ly49L	H-2K^k
Ly49G	H-2D^d, L^d	Ly49P	H-2D^d
Ly49J	H2-K^b	Ly49W	H-2D^d, D^k
Ly49I	H-2D^b, D^d, D^s, D^q, D^v, K^b, K^d, K^s, K^q, K^v, and m157	Ly49R	H-2D^d,D^k,L^d
Ly49J	H-2K^b	CD94/NKG2D	Rae-1, H-60a-c, Mult-1
Ly49O	H-2D^b,D^d,D^k,L^d	CD94/NKG2E	HLA-E
Ly49V	H-2D^b,D^d, K^k	NK1.1	MCMV m12
LILRB1	Overall MHC class I expression	NKp46	Complement factor P, viral hemagglutinin, heparin sulfate
PIR-B	MHC class I	NKR-P1	Clr-b
CD94/NKG2A	Qa1	PIR-A	MHC class I
CD94/NKG2E		DNAM-1	CD155, CD112