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Driver mutations are representative of the genomic landscape of GI stromal tumors. Of the 62 patients with GI stromal tumors with available next generation sequencing, 65 known driver mutations were identified: 41 in KIT, seven in PDGFRA, six in NF1, seven in succinate dehydrogenase (SDH) subunits (A, B, C, or D), two in BRAF, and two in KRAS.
