Fig 3. MOs targeting Islet2a function do not produce significant effects on CaP whole cell voltage-dependent currents.

(A) Recordings were obtained from CaP neurons in 24 hpf uninjected control (grey trace) and morphant (black trace) islet2a embryos. No obvious differences were noted in the amplitudes of peak inward or outward currents. The voltage protocol is as in Fig 2A. (B) The individual values of outward current densities each CaP recorded from in controls (n = 10 cells, 6 embryos) and morphants (n = 8 cells, 8 embryos) are shown. The values for the two groups did not differ significantly (unpaired two-tailed Student t-test: p value, 0.65). (C) Similar to outward current densities, the densities of peak inward currents recorded from CaPs in the control and morphant embryos were not statistically different (unpaired two-tailed Student t-test: p value, 0.51).