Table 6. Univariate analysis for RAGE gene haplotypes, showing association with NASH in obese patients.
NASH (N = 103) vs No Liver Disease (N = 94) | ||||
---|---|---|---|---|
OR | 95% CI | P value | ||
G-T-T-G | Reference | |||
T-T-T-G | 0.65 | 0.28 | 1.49 | 0.14 |
G-T-T-A | 0.92 | 0.32 | 2.58 | 0.65 |
G-T-C-G | 1.30 | 0.73 | 2.33 | 0.57 |
G-A-T-G | 2.08 | 1.21 | 3.58 | 0.006 |
Haplotype Analyses for outcome: (alleles in order rs184003, rs1800624, rs1800625, rs2070600). The major allele in each haplotype is highlighted in bold. OR: Odds ratio; CI: Confidence interval