. 2018 Jun 11;16(6):e2004663. doi: 10.1371/journal.pbio.2004663

Table 1. The IC₅₀ of NBD mimetics.

Inhibitory effects of NBD mimetics on NF-κB activation were measured by luciferase assays at multiple concentrations: 0, 25, 50, 100, and 150 μM. IC₅₀ of NBD mimetics was determined based on the dose-dependent curve by using GraphPad.

NBD Mimetics	IC₅₀ (μM)
SR12460	11.34
SR12454	20.24
SR12343	37.02
SR11481	45.03

Abbreviations: IC₅₀, half maximal inhibitory concentration; NBD, NEMO-binding domain; NEMO, NF-κB essential modulator; NF-κB, nuclear factor κB.

Table 1. The IC50 of NBD mimetics.

Table 1. The IC₅₀ of NBD mimetics.