Table 1.
Recipient and Donor Characteristics Comparing Female Live Donor Recipients by Donor Relationship
| Offspring Donor n = 1,332 |
Non-Offspring Donor n = 1,435 |
P-value | |
|---|---|---|---|
| Recipient Characteristics | |||
| Median age, years (IQR) | 59 (53–65) | 49 (42–57) | <0.001 |
| African American race, N (%) | 369 (28%) | 154 (11%) | <0.001 |
| Median dialysis vintage, days (IQR) | 322 (0–714) | 168 (0–538) | <0.001 |
| Diabetic, N (%) | 524 (40%) | 378 (27%) | <0.001 |
| Cause of end stage renal disease, N (%) | <0.001 | ||
| Diabetes | 385 (29%) | 285 (20%) | |
| Hypertension | 369 (28%) | 209 (15%) | |
| Glomerular disease | 184 (14%) | 319 (22%) | |
| Cystic disease | 110 (8%) | 248 (17%) | |
| Other cause | 195 (15%) | 286 (20%) | |
| Missing | 88 (6%) | 87 (6%) | |
| Any pre-transplant sensitization events, N (%) | 275 (23%) | 324 (25%) | 0.286 |
| Previous kidney transplant, N (%) | 58 (4%) | 123 (9%) | <0.001 |
| Median body mass index, kg/m2 (IQR) | 27.9 (24.2–32.1) | 26.7 (22.7–31.6) | <0.001 |
| Donor Characteristics | |||
| Median age, years (IQR) | 34 (28–40) | 46 (38–53) | <0.001 |
| African American race, N (%) | 376 (28%) | 143 (10%) | <0.001 |
| Male gender, N (%) | 527 (40%) | 493 (34%) | <0.001 |
| Median cold ischemia time, hours (IQR) | 1 (1–2) | 1 (1–2) | 0.738 |
| Median body mass index, kg/m2 (IQR) | 27.1 (24.3–30.7) | 26.2 (23.5–29.5) | <0.001 |
| Median recipient minus donor body mass index (IQR) | 0.5 (−3.7–4.9) | 0.5 (−4.0–5.0) | 0.897 |
| Immunologic Characteristics | |||
| ABO blood type match level | 0.631 | ||
| Identical, N (%) | 1,053 (79%) | 1,117 (78%) | |
| Compatible, N (%) | 262 (20%) | 302 (21%) | |
| Incompatible, N (%) | 17 (1%) | 16 (1%) | |
| CMV risk status | <0.001 | ||
| Recipient positive, N (%) | 910 (75%) | 765 (62%) | |
| Donor and recipient negative, N (%) | 217 (18%) | 264 (21%) | |
| Recipient negative, donor positive, N (%) | 85 (7%) | 208 (17%) | |
| Induction immunosuppression | 0.799 | ||
| Depleting, N (%) | 630 (47%) | 662 (46%) | |
| Non-depleting, N (%) | 372 (28%) | 415 (29%) | |
| None, N (%) | 330 (25%) | 358 (25%) | |
| Calcineurin inhibitor immunosuppression | 0.078 | ||
| Tacrolimus, N (%) | 1,072 (81%) | 1,199 (84%) | |
| Cyclosporine, N (%) | 179 (13%) | 148 (10%) | |
| Both, N (%) | 3 (0%) | 2 (0%) | |
| Neither, N (%) | 78 (6%) | 86 (6%) | |