Higher exploratory locomotion in Ts65Dn mice. Ts65Dn and WT were tested for motor activity during a 60 minute session in automated Accuscan open fields. Significantly higher scores were detected in the Ts65Dn group on parameters of A,B) total distance, C,D) horizontal activity, E,F) vertical activity, G,H) center distance, as totaled across the 60 minute test session (A,C,E,G), and as measured in 5 minute time bins (B,D,F,H). N=8 WT, 10 Ts65Dn, *p < .0.05, **p < 0.01.