Table 3.

Hazard ratios (95% confidence interval) for hip fracture over 15 years of follow-up per 1 kg increase in baseline leg and total lean mass among women in the Framingham Osteoporosis Study (1992–2007)

	Model 1a	Model 2b	Model 3c	Model 4d
Leg lean mass (n=1,978)	0.95 (0.83, 1.08)	1.11 (0.94, 1.31)	1.10 (0.93, 1.30)	1.18 (0.96, 1.44)
Total lean mass (n=1,812)	0.96 (0.92, 1.02)	1.06 (0.99, 1.13)	1.09 (1.02, 1.18)	1.12 (1.04. 1.22)

^aModel 1 unadjusted

^bModel 2 includes age, height, cohort, % body fat

^cModel 3 additionally adjusts for femoral neck BMD

^dModel 4 additionally adjusts for history of hip fracture, smoking, physical activity, estrogen replacement use, osteoporosis medication use