Table 1.
Cohort Demographics and Clinical Variables
| ECMO n=17 |
Inpatient n=48 |
Outpatient n=124 |
Whole Cohort n=189 |
p-value | |
|---|---|---|---|---|---|
|
| |||||
| Age (years) | 46.1 ± 16.6 | 52.9 ± 9.0 | 51.8 ± 11.6 | 51.6 ± 11.6 | 0.11 |
|
| |||||
| Female | 9 (53) | 24 (50) | 52 (42) | 85 (45) | |
| Male | 8 (47) | 24 (50) | 72 (58) | 104 (55) | 0.50 |
|
| |||||
| White | 12 (80) | 26 (59) | 84 (70) | 122 (68) | |
| Black/African American | 1 (7) | 5 (11) | 11 (9) | 17 (9) | |
| Asian | 0 (0) | 2 (5) | 10 (8) | 12 (7) | |
| Hispanic | 2 (13) | 9 (20) | 16 (13) | 27 (15) | |
| Hawaiian/Pac. Islander | 0 (0) | 1 (2) | 0 (0) | 1 (1) | |
| Other | 0 (0) | 1 (2) | 0 (0) | 1 (1) | 0.42 |
|
| |||||
| LAS Group A:COPD | 1 (6) | 4 (8) | 21 (17) | 26 (14) | |
| LAS Group B: PAH | 1 (6) | 1 (2) | 8 (6) | 10 (5) | |
| LAS Group C: CF | 2 (11) | 4 (8) | 17 (14) | 23 (12) | |
| LAS Group D: IPF | 13 (76) | 39 (81) | 78 (63) | 130 (69) | 0.36 |
|
| |||||
| Expired at 1 year | 1 (6) | 2 (4) | 2 (2) | 5 (3) | 0.44 |
|
| |||||
| FEV1 (liters) | 1.7 ± 0.77 | 1.35 ± 0.74 | 1.41 ± 0.70 | 1.43 ± 0.72 | 0.17 |
| FVC (liters | 2.29 ± 0.74 | 1.84 ± 0.89 | 2.07 ± 0.78 | 2.03 ± 0.81 | 0.10 |
| BMI (kg/m2) | 24.5 ± 4.9 | 25.3 ± 4.1 | 25.4 ± 4.4 | 25.3 ± 4.4 | 0.75 |
| 6MWD (meter) | 212 ± 199 | 176 ± 133 | 283 ± 126 | 250 ± 143 | <0.001 |
| LAS | 67.8 ± 26.6 | 69.2 ± 19.4 | 44.5 ± 11.4 | 52.8 ± 19.3 | <0.001 |
Data presented as mean +/−standard deviation or as number of subjects (% of total) Diagnostic indication for transplant as categorized by groupings in the Lung Allocation Score37
Abbreviations: FEV1 (Forced Expiratory Volume, 1 second); FVC (Forced Vital Capacity); BMI (Body Mass Index); 6MWD (six minute walk distance); LAS (Lung Allocation Score); COPD (Chronic Obstructive Pulmonary Disease); PAH (Pulmonary Arterial Hypertension); CF (Cystic Fibrosis); IPF (Idiopathic Pulmonary Fibrosis)