Table 1.

Incidence of PML in MS DMTs

DMT	Cases of PML	PML Patient Age
Natalizumab	763 in >181,300 patientsa	15–73
Fingolimod	19 in >225,000 patientsb*	34–71
Dimethyl Fumarate	5 in >270,000 patientsa*	54–66
Ocrelizumab	0 in >40,000 patientsc*
Teriflunomide	0 in >71,000 patientsd*
Alemtuzumab	0 in >18,400 patientsd*

^*Cases of PML not attributable to prior natalizumab exposure

^aBiogen internal data file,

^bNovartis internal data file,

^cGenentech internal data file,

^dSanofi Genzyme internal data file.