Table 1.
A relationship of tmTNF-α expression and clinical characteristics of ductal breast cancer (n = 105)
| Characteristics | Patients | tmTNF-α expression | p-value | ||||
|---|---|---|---|---|---|---|---|
| Negative | Low | Middle | High | Positive rate (%) | |||
| Age (years) | |||||||
| ≤50 | 63 | 16 | 8 | 26 | 13 | 74.60% | |
| >50 | 42 | 10 | 4 | 20 | 8 | 76.19% | |
| Grade | |||||||
| I | 9 | 3 | 2 | 3 | 1 | 66.67% | |
| II | 88 | 22 | 9 | 37 | 20 | 75.00% | |
| III | 8 | 1 | 1 | 6 | 0 | 87.50% | |
| Tumor Size (cm) | |||||||
| ≤2 | 35 | 15 | 6 | 12 | 2 | 57.14% | 0.002 |
| >2 | 70 | 11 | 6 | 35 | 18 | 83.58% | |
| Node status | |||||||
| Negative (0) | 50 | 17 | 7 | 18 | 8 | 66.00% | 0.0028 |
| Positive (≥1) | 55 | 9 | 5 | 29 | 12 | 83.64% | |
| Estrogen Receptor | |||||||
| Negative | 45 | 5 | 5 | 21 | 14 | 88.89% | 0.0108 |
| Positive | 60 | 21 | 7 | 25 | 7 | 65.00% | |
| Progesterone Receptor | |||||||
| Negative | 52 | 7 | 5 | 26 | 14 | 86.54% | 0.0068 |
| Positive | 53 | 19 | 7 | 20 | 7 | 64.15% | |
| HER 2 | |||||||
| Negative | 67 | 24 | 8 | 24 | 11 | 64.18% | 0.0003 |
| Positive | 38 | 2 | 4 | 22 | 10 | 94.74% | |
| Triple-negative | 25 | 4 | 2 | 12 | 7 | 84.00% | |
| Non-TNBC | 80 | 22 | 10 | 34 | 14 | 72.50% | |
| Total | 105 | 26 | 12 | 46 | 21 | ||
Non-TNBC: Non-triple-negative breast cancer