Table 2.
KEGG-based pathway analysis results from down-regulated genes in KLF10-siRNA treated SiHa cell line obtained from DAVID.
| Category | Term | Count | Genes |
|---|---|---|---|
| KEGG_PATHWAY | hsa05218:Melanoma | 13 | EGFR, BRAF, FGF16, MITF, IGF1, CDH1, FGF12, RB1, PDGFC, FGF1, FGF2, PIK3R1, FGF4 |
| KEGG_PATHWAY | hsa04810:Regulation of actin cytoskeleton | 29 | SSH1, APC2, WASF1, FGF16, IQGAP3, FGF12, ITGB3, DOCK1, TIAM1, ARPC2, ITGAV, ITGB6, PDGFC, FGF1, FGF2, PIK3R1, FGF4, APC, EGFR, BRAF, IGF2, PPP1CB, CHRM5, CFL2, CFL1, ITGA7, CYFIP1, CRK, MYH10 |
| KEGG_PATHWAY | hsa00983:Drug metabolism | 9 | CYP3A5, NAT1, NAT2, CYP2A7, UGT2A3, HPRT1, UGT2B28, IMPDH1, UGT2B7 |
| KEGG_PATHWAY | hsa04060:Cytokine-cytokine receptor interaction | 32 | CXCL1, IFNA21, CNTFR, CXCL11, TNFRSF1A, IL17A, IL1RAP, TPO, CSF2RB, PDGFC, IFNK, IFNA8, PRL, RTEL1, IFNGR1, EGFR, IL6, IL2RA, IL29, TGFBR2, IL25, LIFR, TNFRSF17, EDA2R, CCL4L1, CCL16, CCL11, IFNAR2, CCL13, CXCL13, NGFR, IFNA17 |
| KEGG_PATHWAY | hsa00980:Metabolism of xenobiotics by cytochrome P450 | 10 | CYP3A5, GSTM3, GSTM4, CYP2F1, ADH1B, GSTO1, UGT2A3, UGT2B28, UGT2B7, ALDH3A1 |
| KEGG_PATHWAY | hsa04910:Insulin signaling pathway | 18 | BRAF, PHKB, PRKCI, PRKAB1, PDE3B, IGF2, RPS6, PPP1CB, IRS1, GCK, SLC2A4, PRKAR1B, PKLR, GYS1, SHC1, CRK, CALM2, PIK3R1 |