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. 2018 Jun 21;8:9448. doi: 10.1038/s41598-018-27881-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Enhanced upregulation of reparative genes after FG-aided, epicardial placement of MSCs. Real time RT-PCR analysis detected increased expression of multiple reparative genes in the FG-MSC group, as compared to the Sham (ICM with no treatment), IM-MSC, and FG-Cont (epicardial placement of FG without MSCs) groups at day 3 (left panel) and day 28 (right panel). Relative expression to the Sham group is shown. *p < 0.05 vs. the Sham group, ^† p < 0.05 vs. IM-MSC group. ^§ p < 0.05 vs. FG-Cont group. n = 6 hearts in each group.