Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 22;3:16. doi: 10.1038/s41392-018-0019-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Co-encapsulation of CsA and Gef results in improved therapeutic efficacy in an acquired EGFR-TKI-resistant PC-9-GR tumor-bearing mouse model. a The tumor volume (mm³) change is presented as a function of time after drug treatment. When the tumor volume reached approximately 120 mm³, NP solutions were IV injected three times (indicated by green arrows). Free CsA and/or free Gef were orally administered (shown in red arrows). Saline was intravenously injected as a control. b Body weight gain/loss profiles of mice upon treatment. c Image showing tumors excised from the mice. d The tumor tissue weight on day 18, the endpoint of the study