Fig. 4.

Variant(s) with opposite effects on expression in two cell types. Example of a gene (PNKD) affected by a cis-eQTL in at least two cell types (CD14 and platelets) that are characterized by EAP with ϑ = −0.97, indicating that the gene’s expression level is affected by the same regulatory variant in these two cell types, yet with opposite effects, i.e., the variant that is increasing expression in platelets is decreasing expression in CD14