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. 2018 Feb 17;470(7):1127–1137. doi: 10.1007/s00424-018-2118-z

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Renin mRNA and plasma renin concentration are sensitive to COX-2 inhibition in AS^−/− mice. Kidney renin mRNA abundance (upper panel) and plasma renin concentration (lower panel) in AS^−/− mice and in wild-type controls were measured under basal conditions and after 1 week of SC-236 treatment. Data are means ± SEM of 6 mice of each genotype. Asterisks indicate p < 0.05