Fig. 3.

Differential expression of VSELs mRNA. a Heat map showing in red the main induced genes in VSELs by comparison to control cells (log₂ fold change higher than five), and the most downregulated gene in green (log₂ fold change higher than eight). b Heat map showing a comparison between gene expression variations in VSELs relative to control cells (present study) and those observed regularly in embryonic stem cells during maintenance, arrows annotated the genes with a significant discrepancy (green is a decrease and red is increase relative to control). The color scale is shown at the bottom. c Classification by their function or their localization of the differentially expressed genes observed by RNA-Seq