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. 2018 Jun 15;12:407. doi: 10.3389/fnins.2018.00407

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Copyright © 2018 Ham, Kim, Hong, Kim, Tang and Im.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagram displaying numbers of upregulated and downregulated SCZ-associated genes in AD animal model. The left Venn diagrams show differently expressed cortical mRNAs of AD mice compared to control mice and the right Venn diagrams show differently expressed hippocampal mRNAs of AD mice compared to control mice (P-value < 0.05, Fold change > 1.3). (A) The number of significantly altered genes within five GO terms associated with SCZ. (B) The number of significantly altered genes within four GO terms associated with BIP. (C) The number of significantly altered genes within five GO terms associated with MDD. Italicization denotes the number of up-regulated genes and an underline denotes the number of down-regulated genes. Numbers in red indicate the number of contra-regulated genes that are upregulated in one group and downregulated in another group.