Table 2.
Univariate and multivariate factors associated with CHD mortality in DFH plus PFH patients combined.
| Variable | Univariate associations with CHD death |
Multivariable model including all variables |
Model selected using stepwise Cox regression |
||||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | ||
| Age (years) | Per 10years | 1.87 (1.57–2.21) | <0.0001 | 1.49 (1.21–1.83) | 0.0001 | 1.52 (1.26–1.82) | <0.0001 |
| Sex | F:M | 0.45 (0.34–0.58) | <0.0001 | 0.48 (0.35–0.65) | <0.0001 | 0.49 (0.37–0.64) | <0.0001 |
| Ever smoker | Y:N | 1.96 (1.51–2.54) | <0.0001 | 1.70 (1.26–2.30) | 0.0005 | 1.60 (1.22–2.10) | 0.001 |
| Diabetes | Y:N | 2.03 (1.00–4.10) | 0.05 | 1.91 (0.70–5.19) | 0.207 | ||
| Total cholesterol (mmol/l) | Per SD | 1.37 (1.23–1.52) | <0.0001 | 1.39 (1.24–1.56) | <0.0001 | 1.40 (1.26–1.55) | <0.0001 |
| BMI (kg/m2) | Per SD | 1.12 (0.97–1.30) | 0.128 | 1.08 (0.89–1.30) | 0.441 | ||
| SBP (mmHg) | Per SD | 1.09 (0.96–1.25) | 0.198 | 1.07 (0.92–1.25) | 0.381 | ||
| Prior CHD | Y:N | 5.76 (4.38–7.57) | <0.0001 | 4.19 (3.05–5.74) | <0.0001 | 4.33 (3.24–5.80) | <0.0001 |
| Diagnosis | DFH:PFH | 1.37 (1.07–1.77) | p = 0.013 | 1.32 (0.98–1.77) | 0.072 | ||