Table 3.

Observed and expected CHD and Total deaths by time period in DFH vs PFH patients (all ages).

	Total Pyrs	From 1 January 1980 to 31 December 1991					Total Pyrs	From 1 January 1992 to December 2008
		Observed	Expected	SMR	95% CI	p-value		Observed	Expected	SMR	95% CI	p-value
DFH patients
Coronary heart disease	3887	24	6.72	357	(229, 531)	<0.0001	23,278	98	39.96	245	(199, 299)	<0.0001
All cause of death	3887	37	23.69	156	(110, 215)	0.01	23,278	194	192.77	100	(87,116)	0.95
PFH patients
Coronary heart disease	2740	12	4.58	262	(135, 458)	0.0005	19,839	64	39.44	162	(125, 207)	0.0004
All-causes of death	2740	17	16.80	101	(59, 162)	1.00	19,839	162	192.28	84	(72, 98)	0.03

	Total Pyrsa	From 1 January 2009 to 31 December 2015					p-value trend
		Observed	Expected	SMR	95% CI	p-value
DFH patients
Coronary heart disease	9460	27	11.92	227	(149, 330)	0.0002	0.16
All-causes of death	9460	84	78.66	107	(85, 132)	0.0.58	0.25
PFH patients
Coronary heart disease	7857	27	11.31	239	(157, 347)	0.0001	0.70
All-causes of death	7857	91	74.42	122	(98, 150)	0.07	0.02

^aPys = person years exposure.