Table 4.

Observed and expected CHD deaths by time period in DFH males and females (all ages) with and without CHD at registration.

	Total Pyrs	From 1 January 1980 to 31 December 1991					Total Pyrs	From 1 January 1992 to December 2008
		Observed	Expected	SMR	95% CI	p-value		Observed	Expected	SMR	95% CI	p-value
Male patients
CHD	616	10	2.07	483	(232, 589)	0.0001	2940	50	10.7	466	(346, 614)	<0.0001
No CHD	1444	5	2.53	197	(64, 460)	023	8557	17	14.28	119	(69, 191)	0.54
Female patients
CHD	417	6	0.83	723	(265, 1573)	0.0004	1948	20	4.53	442	(270, 682)	<0.0001
No CHD	1410	3	1.29	233	(48, 681)	0.28	9832	11	10.4	105	(53, 189)	0.94

	Total Pyrs	From 1 January 2009 to 31 December 2015					p-value trend
		Observed	Expected	SMR	95% CI	p-value
Male patients
CHD	975	7	2.79	251	(101, 517)	0.035	0.11
No CHD	3823	5	5.6	89	(29, 208)	0.99	0.27
Female patients
CHD	535	4	0.77	516	(141, 1323)	0.016	0.50
No CHD	4127	10	2.74	366	(165, 672)	0.001	0.16