FIG 1.

Effects of ETEC strain H10407 infection in antibiotic-pretreated mice fed a nourished diet (HC), a protein-deficient diet (dPD), or a zinc-deficient diet (dZD). Mice were fed one of the three diets (HC, dPD, or dZD) for 2 weeks and pretreated with an antibiotic cocktail prior to infection with 10⁸ CFU of ETEC strain H10407. (A) Body weight change postchallenge. Daily weight measures were collected after infection. *, P < 0.01 (HC versus HC plus ETEC during days 1 to 7 postinfection); **, P < 0.005 (dZD versus dZD plus ETEC during days 2 to 7 postinfection) (n = 8/group); ***, P < 0.05 (dPD versus dPD plus ETEC during days 1 to 3 postinfection). (B) Stool ETEC H10407 shedding. Quantitative PCR was performed using DNA samples that had been extracted from stool samples from ETEC-infected mice (n = 8/group).