FIG 7.

Zinc supplementation decreases intestinal colonization by the ETEC LT mutant of H010407 (LTKO) in zinc-deficient infected C57/BL6 mice. Zinc-deficient mice received supplemental zinc sulfate in drinking water (150 mg/liter) starting from day 12 post-ETEC infection. Quantitative PCR was performed using DNA samples that had been extracted from stool samples or intestine samples from infected mice. (A) Effect of zinc supplementation on stool ETEC LTKO shedding after 13 days of zinc treatment (day 25 postinfection). (B) Effect of zinc supplementation on colon and ileum ETEC LTKO colonization after 13 days of zinc treatment (day 25 postinfection) (n = 4/group).