Table 1.
Baseline population characteristics by genetic variants at CD36, NOS3 and PPARG.a
|
CD36 (rs1527483) |
NOS3 (rs1799983) |
PPARG (rs1801282) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Omega-3 supplements |
Control |
Omega-3 supplements |
Control |
Omega-3 supplements |
Control |
|||||||
| AA/AG (n = 41) | GG (n = 55) | AA/AG (n = 19) | GG (n = 31) | AA/AC (n = 10) | CC (n = 90) | AA/AC (n = 11) | CC (n = 39) | GG/GC (n = 12) | CC (n = 88) | GG/GC (n = 5) | CC (n = 45) | |
| Age, y | 59.2 (10.9) | 60.6 (9) | 59.5 (10.6) | 58.1 (10.5) | 62.4 (9.4) | 59.8 (10) | 55.5 (9.7) | 59.5 (10.6) | 60 (9) | 60.1 (10.1) | 50.8 (10.4) | 59.5 (10.2) |
| Women, % | 53.7 | 54.6 | 52.6 | 51.6 | 80 | 52.2 | 27.3 | 59 | 75 | 52.3 | 20 | 55.6 |
| BMI, kg/m2 | 25.4 (3.9) | 24.2 (2.9) | 25.6 (3.3) | 25.9 (4.8) | 24.6 (1.8) | 24.8 (3.6) | 26.7 (7.6) | 25.5 (3) | 25.3 (2.9) | 24.7 (3.5) | 23.2 (3.4) | 26.1 (4.3) |
| HbA1c, % | 8.0 (1.9) | 8.2 (2.3) | 7.9 (2) | 7.2 (1.2) | 9.1 (2.3) | 8.0 (2.1) | 7.8 (2.2) | 7.4 (1.4) | 7.8 (1.4) | 8.1 (2.2) | 8.4 (2.5) | 7.4 (1.4) |
| SBP, mmHg | 142 (20) | 135 (18) | 141 (27) | 130 (15) | 136 (16) | 138 (19) | 124 (14) | 137 (22) | 135 (17) | 138 (19) | 120 (4) | 136 (21) |
| DBP, mmHg | 82 (9) | 77 (10) | 86 (20) | 76 (10) | 75 (9) | 79 (10) | 77 (7) | 81 (17) | 78 (11) | 79 (10) | 76 (8) | 81 (16) |
| HDL-C, mmol/L | 1.15 (0.31) | 1.17 (0.31) | 1.24 (0.21) | 1.14 (0.16) | 1.13 (0.3) | 1.17 (0.31) | 1.17 (0.15) | 1.18 (0.2) | 1.2 (0.28) | 1.16 (0.31) | 1.22 (0.13) | 1.18 (0.19) |
| LDL-C, mmol/L | 3.07 (0.78) | 2.81 (0.87) | 3.30 (1.02) | 2.94 (0.75) | 3.02 (0.69) | 2.94 (0.86) | 2.84 (0.54) | 3.14 (0.94) | 3.35 (0.77) | 2.90 (0.84) | 2.77 (0.58) | 3.11 (0.89) |
| TC, mmol/L | 4.84 (0.86) | 4.53 (0.96) | 5.17 (1.08) | 4.72 (0.99) | 4.72 (0.98) | 4.71 (0.95) | 4.66 (0.80) | 4.95 (1.10) | 5.23 (1.18) | 4.64 (0.89) | 4.60 (0.81) | 4.92 (1.06) |
| TC/HDL-C | 4.40 (1.03) | 4.05 (1.12) | 4.29 (1.18) | 4.14 (0.79) | 4.30 (0.92) | 4.24 (1.13) | 4.02 (0.70) | 4.25 (1.00) | 4.49 (0.99) | 4.21 (1.13) | 3.75 (0.28) | 4.24 (0.98) |
| TG, mmol/L | 1.74 (0.83) | 1.71 (1.00) | 1.94 (0.87) | 1.81 (0.91) | 1.78 (0.8) | 1.73 (0.94) | 1.71 (0.70) | 1.90 (0.94) | 2.02 (1.22) | 1.70 (0.87) | 1.83 (0.82) | 1.86 (0.90) |
BMI, body mass index; HbA1c, glycated haemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides.
a
Values are presented as mean (SD) or as percentage.