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. 2018 Jun 15;9:634. doi: 10.3389/fphar.2018.00634

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Copyright © 2018 Huang, Li, Li, Fan, Zhuang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impaired cardiac histomorphology and myocardial apoptosis were ameliorated by ginseng compatibility environment. (A) The change of morphology of transversal septal sections of hearts and right ventricle (RV), magnification 200×. (B,C) Myocardial apoptosis: DNA fragmentation of apoptotic cells was detected by TUNEL staining in myocardium and the apoptosis rates in different groups were calculated, magnification 400×. (D–F) Apoptosis-related mRNA: Bax, Bcl-2, and the ration of Bcl-2 to Bax in RVs. The values represent means ± SEM. ^∗P < 0.05, ^∗∗P < 0.01 vs. Con; ^#P < 0.05, ^##P < 0.01 vs. Mod; ^$P < 0.05, ^$$P < 0.01 vs. FBC.