Table 4.
All cytokine differences over time are represented as least-square mean estimates and standard errors. All test results are performed using estimates from a repeated measures mixed-effects linear regression controlling for reliability and viability.
| Estimate (Post-Pre) | Standard Error | p-value | ||
|---|---|---|---|---|
| Fresh | Th1/Th2 | −4.00 | 5.36 | 0.46 |
| Th1 | 2.28 | 3.38 | 0.50 | |
| Th2 | 2.70 | 1.17 | 0.0336 | |
| Th17 | −0.14 | 0.26 | 0.60 | |
| Tr1 | −0.88 | 1.53 | 0.57 | |
| Treg | −1.10 | 2.62 | 0.67 | |
| Cryopreserved | Th1/Th2 | −10.69 | 5.36 | 0.06 |
| Th1 | −9.19 | 3.38 | 0.0142 | |
| Th2 | 10.08 | 1.17 | <0.0001 | |
| Th17 | 0.58 | 0.26 | 0.0405 | |
| Tr1 | −7.73 | 1.53 | <0.0001 | |
| Treg | 11.11 | 2.62 | 0.0005 |
Bold: p < 0.05; Bold and italicized: p < 0.05/14 = 0.0017.