TABLE 1.
Characteristics of COMET Participants with Axial Length Curves (N = 431).
| Characteristic | Overall | Younger Cohort |
Older Cohort |
Axial Stabilized at Baseline |
Axial Not Stabilized |
P Valuea |
|---|---|---|---|---|---|---|
| n = 431 | n = 30 | n = 334 | n = 19 | n=48 | ||
|
| ||||||
| Baseline Age | ||||||
| Mean (SD) | 9.81 (1.31) | 7.41 (0.51) | 10.06 (1.06) | 11.05 (0.85) | 9.08 (1.41) | <0.0001 |
| n (%) | n (%) | n (%) | n (%) | n (%) | ||
|
|
||||||
| Ethnicity | 0.69 | |||||
| African-American | 115 (27) | 10 (33) | 88 (26) | 9 (47) | 8 (17) | |
| Asian | 33 (8) | 2 (7) | 26 (8) | 1 (5) | 4 (8) | |
| Hispanic | 63 (15) | 3 (10) | 49 (15) | 1 (5) | 10 (21) | |
| Mixed | 22 (5) | 1 (3) | 17 (5) | 1 (5) | 3 (6) | |
| White | 198 (46) | 14 (47) | 154 (46) | 7 (37) | 23 (48) | |
| Sex | 0.69 | |||||
| Male | 202 (47) | 11 (37) | 158 (47) | 9 (47) | 24 (50) | |
| Female | 229 (53) | 19 (63) | 176 (53) | 10 (53) | 24 (50) | |
| Number of Myopic parentsb | 0.47 | |||||
| None | 35 (16) | 2 (17) | 29 (16) | 0 (0) | 4 (15) | |
| 1 | 106 (47) | 4 (33) | 87 (49) | 3 (33) | 12 (44) | |
| 2 | 84 (37) | 6 (50) | 61 (34) | 6 (67) | 11 (41) | |
Younger cohort: children with baseline age of 6–7 years and axial elongation after baseline.
Older cohort: children with baseline age ≥8 years and axial elongation after baseline.
Axial Length Stabilized at Baseline cohort: the annual change rates of axial elongation at all visits < 0.06mm/year.
Axial Length Not Stabilized cohort: the annual change rates of axial elongation at all visits > 0.06mm/year.
a
based on ANOVA/Chi-square tests comparing means/proportions across four groups for baseline age, ethnicity, sex, treatment group and the number of myopic parents.
b
Based on a subset of participants with parental myopia data (n=225).